I would say yes. The typical B/X-alike that the OSR was built on features a number of tools that encourage navigation, resource management, and careful planning. Those tools can be applicable anywhere adn turn any environment into a sort of “dungeon.” There are city kits and tools that treat navigating a city like a dungeon (Electric Bastionland is a recent example).
So yes, in that the tools the OSR scene typically provides can be used for a multitude of navigation/resource/problem-solving challenges. They’re usually used with “dungeon vocabulary” but can be applied anywhere.